- Abnormal brain function (uremic encephalopathy)
- Certain other severe symptoms, such as loss of appetite or vomiting with weight loss
- Inflammation of the sac around the heart (pericarditis)
- A high level of acid in the blood (acidosis) that does not respond to other treatments
- Heart failure
- Total body fluid overload
- Fluid overload in the lungs (pulmonary edema) that does not respond to other treatments
- A very high level of potassium in the blood (hyperkalemia)
- A high level of calcium in the blood (hypercalcemia)
- Greatly reduced kidney function
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